What is immunoglobulin?

Immunoglobulins are proteins made by the immune system to fight infection. Immunoglobulin products are purified from blood donations and are used to treat a variety of medical conditions.

Who needs Immunoglobulin treatment?

Replacement doses of immunoglobulin are given when he body does not make enough of its own to fight infection.

High doses of immunoglobulin may be given to help control some inflammatory conditions.

How is Immunoglobulin given?

Immunoglobulin is given either by a drip into the vein (intravenous administration /IVIG) or by infusion under the skin (subcutaneous administration/SCIG). If long term treatment is required, immunoglobulin can be given at home. Ask your doctor/nurse about this.

What about side effects?

Side effects are usually mild, but you may be more likely to experience these if you receive immunoglobulin while you have an infection.  Please let your nurse know if you have been unwell before starting any infusion.

During / soon after the infusion:

Headache, temperature, muscle pain and low back pain can occur. These are usually mild and self limiting.  On occasions, taking paracetamol or slowing of the rate of infusion is required.

Allergic reactions: 

These may include skin rashes.  More severe reactions are uncommon. 

Local skin swelling:

This occurs where subcutaneous immunoglobulin has been infused. This is simply due to fluid accumulation and resolves over 24 hours.

Other recognised side effects:

Very rarely kidney problems, blood clots and a rare form of non infectious meningitis may occur as a complication of treatment.